AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery
Adeno-associated virus (AAV) vectors are among the most widely used delivery vehicles for in DINING CHAIR vivo gene therapy as they mediate robust and sustained transgene expression with limited toxicity.However, a significant impediment to the broad clinical success of AAV-based therapies is the widespread presence of pre-existing humoral immunity